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Keywords

Papillon-LeFevre Syndrome (PLS), alveolar bone loss, localized aggressive periodontitis, palmar-plantar hyperkeratosis

Abstract

Papillon-LeFevre Syndrome (PLS) is a rare autosomal recessive disease, associated with palmar-plantar hyperkeratosis and premature loss of both deciduous and permanent teeth. Treatment of this disease continues to be a challenge to the medical and dental professions. The following is a case report of two siblings of Chinese origin, diagnosed with Papillon-LeFevre syndrome and follows them for 10 subsequent years.

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